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Taurine for Testosterone: An underused Key for Natural ‘T’

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Taurine for Tesosterone’ is not a proposition we hear often. Just browse the ingredients of a dozen supplements purported to “boost testosterone” and you’re unlikely to find taurine in many (if not ‘any’) of them.

That’s interesting because ‘taurine for testosterone’ is no more an outlandish hypothesis than the male hormone being allegedly raised by any number of ingredients in your “best-selling” T-boosters.

Take tribulus terrestris for example. It’s an herb that’s been all but proven completely dead as a testosterone booster. The evidence against its effectiveness is greater than that for it. But it keeps being added to products, a practice that I think lowers the credibility of the companies selling them. taurine-supplement

So why not taurine for testosterone? It’s an amino acid-like substance that appears to be produced by the body in lesser amounts with age. It can help to lower blood pressure. It’s been used successfully to help treat congestive heart failure.

And in animal studies, it’s been shown to boost testosterone.

Could taurine be a viable component in a good T-boosting strategy?

 

Taurine: What exactly is this stuff?

Technically, it’s not an amino acid. That’s because amino acids are the building blocks of protein. They contain a carboxyl group on the far side of an amino group flanking a carbon atom.

In place of the carboxyl group, taurine has sulfonyl hydroxide. This makes it a little more acid-y than your typical amino acid.

But since most of us aren’t chemists, we just classify it as an amino acid because it’s darn close to being one.

And classified as such, taurine is designated a non-essential amino acid. That means most of us don’t need to get it from our diets because it’s manufactured in our bodies. This biosynthesis occurs mostly in the pancreas and starts with the amino acid cysteine.

But taurine is also acquired from outside the body from foods such as fish and meat. Those have relatively high amounts of it. Dietary sources tend to provide about 55 to 60 mg. per day.

The biggest human concentrations of taurine occur in the brain, retina, gastrointestinal tract, muscle tissue, blood cells, and heart.

 

Taurine for Testosterone: A ‘Stimulator’ at the Cellular Level?

Taurine is also produced by and present in the testes of adult males. Apparently, it’s needed there for… something, but nobody knows exactly ‘what.’

Based on some rodent studies, it just might be needed for ‘T’ production. If you give lab rats taurine in their drinking water for a couple months, their testosterone, luteinizing hormone, and FSH rise considerably. Researchers suspect that taurine increases the number of receptors for hormone producing cells.
What’s the catch?

The catch is that the animals were given high doses. The human equivalent of the amount of taurine given to these ‘raging bull’ rats was anywhere from 5 to 8 grams a day.
That’s a lot. Human experiments have generally been with doses no higher than 3 grams per day. This amount has been deemed fairly safe over the long run. Researchers don’t really know how the body might react to long-term higher doses of taurine.

Incidentally, people who drink 7 or 8 Red Bull ‘energy drinks’ a day are making themselves human guinea pigs for long-term effects of multi-gram daily taurine intake.

 

Taurine for Testosterone: Some Protection for the ‘Production Plant’

For what it’s worth, another study revealed that rats given the human equivalent of 1500 mg of taurine per day were significantly protected against the testes-damaging effects of steroids.

 

testosterone-molecule

In that study, some rats were given weekly injections of the human equivalent of a weekly dose 140 mg nandrolone decanoate (steroid). Another group was given the same dose of the steroid along with the 1.5 grams of daily taurine. A control group was given only taurine while another control group were given nothing.

As suspected, the steroid-taking rats experienced considerable suppression of functioning in their testes. The drug reduced the production of enzymes involved in the biosynthesis of testosterone, such as 3- and 17-beta-HSD. It also shrunk the size of the testes. These were two effects that were reduced but not prevented with taurine.

But the taurine completely eliminated other steroid side effects. One of these was the reduction of glutathione, a major antioxidant. The steroid only rats had a huge drop in glutathione concentration in the testes. The taurine prevented this in the group that got the amino acid along with their injections.

There was more production of inflammatory proteins in the steroid using rats – but not in the taurine/steroid using rats.

More genetic damage occurred in the steroids-only rats – but not in the taurine/steroids rats.

In the steroids-only rats, there was increased production of caspase-3 leading to higher asposis (cell death). The taurine prevented this in those rats that received it with steroids.

 

Taurine: Antioxidant Protection where it Counts?

My emphasis on the taurine-steroids study is not for the purpose of condoning steroid use in conjunction with taurine. Nonetheless, it’s obvious if a guy chooses to use steroids, he might be better off using taurine with them.

To me, the study raises a different hypothesis – that of taurine being a necessary antioxidant for testosterone protection/enhancement as we age. If it provides the testes some protection against a drug-induced bio-oxidative attack, how much more could it provide against the mundane oxidation of daily function?

I’ve added two grams per day to my antioxidant stack. I’ll update you on any effects over time.

If nothing else, I’ve noticed taurine’s subtle calming effect – something that might be of aid in controlling cortisol. This, by itself, could help improve body composition and testosterone over time.

 

References

Yang J, Lin S, Feng Y, Wu G, Hu J. Taurine Enhances the Sexual Response and Mating Ability in Aged Male Rats. Advances in Experimental Medicine and Biology. (Vol 776, pp 347-355) Jan. 2013

Yang J, Wu G, Feng Y, Sun C, Lin S, Hu J. CSD mRNA expression in rat testis and the effect of taurine on testosterone secretion. Amino Acids (Vol 39, issue 1, pp 155–160) June 2010

Ahmed MA. Amelioration of nandrolone decanoate-induced testicular and sperm toxicity in rats by taurine: Effects on steroidogenesis, redox and inflammatory cascades, and intrinsic apoptotic pathway. Toxicology and Applied Pharmacology (Vol 282, Issue 3, pp 285–296) Feb. 2015

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